A Draft of methods used in research (the topic about SICKLE CELL ANEMIA)

i need to make (A DRAFT METHODS OF RESEARCH ) about SICKLE CELL ANEMIA .The draft include ( methods of research that will be used in research ), material and methods.1- research design2-reasearch setting .3- research subjects and sampling : study sample , sample use , tools of data collection* validity and reliability* pilot study* data collection process*ethical considerations and human right*statistical analysis*result*discussion*conclusion and recommendation*reference* fill the management table .Topic: sickle cell anemiaResearch problem: sickle cell diseaseswhat are the relationship between environmental effecter and Sickle cell patient ?Aims and impact of the study :-For compare the cases in winter and other seasonFor compare the result of sickle cell patient .for avoid to spread sickle cell disease in eastern of Saudi Arabia(Alahssa ).For awareness sickle cell patient (community culture ) about whether effector.finally the study will be in  King fahad hospital .